IgG-Assisted Age-Dependent Clearance of Alzheimer's Amyloid β Peptide by the Blood–Brain Barrier Neonatal Fc Receptor

The role of blood–brain barrier (BBB) transport in clearance of amyloid β-peptide (Aβ) by Aβ immunotherapy is not fully understood. To address this issue, we studied the effects of peripherally and centrally administered Aβ-specific IgG on BBB influx of circulating Aβ and efflux of brain-derived Aβ...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Deane, Rashid, Sagare, Abhay, Hamm, Katie, Parisi, Margaret, LaRue, Barbra, Guo, Huang, Wu, Zhenhua, Holtzman, David M., Zlokovic, Berislav V.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726020/
https://ncbi.nlm.nih.gov/pubmed/16354907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3697-05.2005
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