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Biochemistry of Amyloid β-Protein and Amyloid Deposits in Alzheimer Disease

Progressive cerebral deposition of the amyloid β-protein (Aβ) in brain regions serving memory and cognition is an invariant and defining feature of Alzheimer disease. A highly similar but less robust process accompanies brain aging in many nondemented humans, lower primates, and some other mammals....

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Detalhes bibliográficos
Main Authors: Masters, Colin L., Selkoe, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367542/
https://ncbi.nlm.nih.gov/pubmed/22675658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a006262
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