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The AMY Antigen Co-Occurs with Aβ and Follows Its Deposition in the Amyloid Plaques of Alzheimer’s Disease and Down Syndrome

Novel plaque-like “AMY” lesions were recently described in the brains of patients with Alzheimer’s disease (AD). Using three Aβ antibodies, we now document the co-occurrence of AMY immunoreactivity (IR) with amyloid β-peptide (Aβ) in the large majority of plaques in AD brain. AMY IR was detected in...

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Detalhes bibliográficos
Main Authors: Lemere, Cynthia A., Grenfell, Trelawney J., Selkoe, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866646/
https://ncbi.nlm.nih.gov/pubmed/10393833
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