Temporal Accrual of Complement Proteins in Amyloid Plaques in Down’s Syndrome with Alzheimer’s Disease

The complement system constitutes a series of enzymatic steps involved in the inflammatory response and is activated in Alzheimer’s disease (AD). Using Down’s syndrome (DS) brains as a temporal model for the progression of AD, we examined components of the complement cascade and their relationship t...

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Main Authors: Stoltzner, Sarah E., Grenfell, Trelawney J., Mori, Chica, Wisniewski, Krystyna E., Wisniewski, Thomas M., Selkoe, Dennis J., Lemere, Cynthia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850044/
https://ncbi.nlm.nih.gov/pubmed/10666378
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