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Immune hyporesponsiveness to amyloid β-peptide in amyloid precursor protein transgenic mice: Implications for the pathogenesis and treatment of Alzheimer's disease

Alzheimer's disease is a dementia that involves progressive deposition of amyloid β-protein (Aβ) in brain regions important for memory and cognition, followed by secondary inflammation that contributes to the neuropathologic process. Immunization with Aβ can reduce cerebral Aβ burden and consequent...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Monsonego, Alon, Maron, Ruth, Zota, Victor, Selkoe, Dennis J., Weiner, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11517335/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.191118298
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