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Immune hyporesponsiveness to amyloid β-peptide in amyloid precursor protein transgenic mice: Implications for the pathogenesis and treatment of Alzheimer's disease

Alzheimer's disease is a dementia that involves progressive deposition of amyloid β-protein (Aβ) in brain regions important for memory and cognition, followed by secondary inflammation that contributes to the neuropathologic process. Immunization with Aβ can reduce cerebral Aβ burden and conseq...

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Autors principals: Monsonego, Alon, Maron, Ruth, Zota, Victor, Selkoe, Dennis J., Weiner, Howard L.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC56951/
https://ncbi.nlm.nih.gov/pubmed/11517335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191118298
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