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Brains from non-Alzheimer’s individuals containing amyloid deposits accelerate Aβ deposition in vivo

BACKGROUND: One of the main features of Alzheimer’s disease (AD) is the presence of Aβ deposits, which accumulate in the brain years before the onset of symptoms. We and others have demonstrated that cerebral Aβ-amyloidosis can be induced in vivo by administration of AD-brain extracts into transgeni...

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Detalhes bibliográficos
Main Authors: Duran-Aniotz, Claudia, Morales, Rodrigo, Moreno-Gonzalez, Ines, Hu, Ping Ping, Soto, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046659/
https://ncbi.nlm.nih.gov/pubmed/24252208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-76
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