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Light-Controllable PROTACs for Temporospatial Control of Protein Degradation

PROteolysis-TArgeting Chimeras (PROTACs) is an emerging and promising approach to target intracellular proteins for ubiquitination-mediated degradation, including those so-called undruggable protein targets, such as transcriptional factors and scaffold proteins. To date, plenty of PROTACs have been...

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Bibliografske podrobnosti
izdano v:Front Cell Dev Biol
Main Authors: Liu, Jing, Peng, Yunhua, Wei, Wenyi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326567/
https://ncbi.nlm.nih.gov/pubmed/34350175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.678077
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