SUMOylated non-canonical polycomb PRC1.6 complex as a prerequisite for recruitment of transcription factor RBPJ

BACKGROUND: Notch signaling controls cell fate decisions in many contexts during development and adult stem cell homeostasis and, when dysregulated, leads to carcinogenesis. The central transcription factor RBPJ assembles the Notch coactivator complex in the presence of Notch signaling, and represse...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Sotomska, Małgorzata, Liefke, Robert, Ferrante, Francesca, Schwederski, Heiko, Oswald, Franz, Borggrefe, Tilman
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325870/
https://ncbi.nlm.nih.gov/pubmed/34332624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-021-00412-9
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