SUMOylated non-canonical polycomb PRC1.6 complex as a prerequisite for recruitment of transcription factor RBPJ

BACKGROUND: Notch signaling controls cell fate decisions in many contexts during development and adult stem cell homeostasis and, when dysregulated, leads to carcinogenesis. The central transcription factor RBPJ assembles the Notch coactivator complex in the presence of Notch signaling, and represse...

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Detalles Bibliográficos
Publicado en:Epigenetics Chromatin
Autores principales: Sotomska, Małgorzata, Liefke, Robert, Ferrante, Francesca, Schwederski, Heiko, Oswald, Franz, Borggrefe, Tilman
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325870/
https://ncbi.nlm.nih.gov/pubmed/34332624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-021-00412-9
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