Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing

Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin modifications to enforce gene silencing, but how transcriptional repression is propagated through mitotic cell divisions remains a...

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發表在:Nat Commun
Main Authors: Moussa, Hagar F., Bsteh, Daniel, Yelagandula, Ramesh, Pribitzer, Carina, Stecher, Karin, Bartalska, Katarina, Michetti, Luca, Wang, Jingkui, Zepeda-Martinez, Jorge A., Elling, Ulrich, Stuckey, Jacob I., James, Lindsey I., Frye, Stephen V., Bell, Oliver
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488670/
https://ncbi.nlm.nih.gov/pubmed/31036804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09628-6
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