Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing

Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin modifications to enforce gene silencing, but how transcriptional repression is propagated through mitotic cell divisions remains a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Moussa, Hagar F., Bsteh, Daniel, Yelagandula, Ramesh, Pribitzer, Carina, Stecher, Karin, Bartalska, Katarina, Michetti, Luca, Wang, Jingkui, Zepeda-Martinez, Jorge A., Elling, Ulrich, Stuckey, Jacob I., James, Lindsey I., Frye, Stephen V., Bell, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488670/
https://ncbi.nlm.nih.gov/pubmed/31036804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09628-6
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