Stereoselective synthesis of novel 2′-(S)-CCG-IV analogues as potent NMDA receptor agonists

We developed a versatile stereoselective route for the synthesis of new 2′-(S)-CCG-IV analogues. The route allows for late stage diversification and thereby provides access to a great variety of conformationally restricted cyclopropyl glutamate analogues. A selection of the 2′-(S)-CCG-IV analogues w...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Eur J Med Chem
Main Authors: Maolanon, Alex, Papangelis, Athanasios, Kawiecki, David, Mou, Tung-Chung, Syrenne, Jed T., Yi, Feng, Hansen, Kasper B., Clausen, Rasmus P.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325387/
https://ncbi.nlm.nih.gov/pubmed/33383257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.113099
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares