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Genome-wide reduction in chromatin accessibility and unique transcription factor footprints in endothelial cells and fibroblasts in scleroderma skin
OBJECTIVE: Systemic sclerosis (SSc) is characterized by widespread fibrosis and vascular complications. In this study, we utilized an assay for genome-wide chromatin accessibility to examine the chromatin landscape and transcription factor footprints in SSc. METHODS: Dermal endothelial cells (ECs) a...
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| Publicat a: | Arthritis Rheumatol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8324511/ https://ncbi.nlm.nih.gov/pubmed/33586346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41694 |
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