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Dissecting the cellular mechanism of prostacyclin analogue iloprost in reversing vascular dysfunction in scleroderma
OBJECTIVES. Intravenous iloprost improves Raynaud’s phenomenon (RP) and promotes healing of digital ulcers (DU) in scleroderma (SSc). Despite a short half-life, its clinical efficacy lasts weeks. Endothelial adherens junctions, which are formed by VE-cadherin clustering between endothelial cells (EC...
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| Udgivet i: | Arthritis Rheumatol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7914149/ https://ncbi.nlm.nih.gov/pubmed/33001586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41536 |
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