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CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity

The prognosis of patients with acute myeloid leukemia (AML) remains dismal, highlighting the need for novel innovative treatment strategies. The application of chimeric antigen receptor (CAR) T-cell therapy to patients with AML has been limited, in particular by the lack of a tumor-specific target a...

詳細記述

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書誌詳細
出版年:Blood
主要な著者: Sauer, Tim, Parikh, Kathan, Sharma, Sandhya, Omer, Bilal, Sedloev, David, Chen, Qian, Angenendt, Linus, Schliemann, Christoph, Schmitt, Michael, Müller-Tidow, Carsten, Gottschalk, Stephen, Rooney, Cliona M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323977/
https://ncbi.nlm.nih.gov/pubmed/34323938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008221
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