Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1

The successful immunotherapy of acute myeloid leukemia (AML) has been hampered because most potential antigenic targets are shared with normal hematopoietic stem cells (HSCs), increasing the risk of sustained and severe hematopoietic toxicity following treatment. C-type lectin-like molecule 1 (CLL-1...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Tashiro, Haruko, Sauer, Tim, Shum, Thomas, Parikh, Kathan, Mamonkin, Maksim, Omer, Bilal, Rouce, Rayne H., Lulla, Premal, Rooney, Cliona M., Gottschalk, Stephen, Brenner, Malcolm K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589064/
https://ncbi.nlm.nih.gov/pubmed/28676343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.05.024
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