CD7 CAR T Cells for the Therapy of Acute Myeloid Leukemia

Chimeric antigen receptor (CAR) T cell therapy for the treatment of acute myeloid leukemia (AML) has the risk of toxicity to normal myeloid cells. CD7 is expressed by the leukemic blasts and malignant progenitor cells of approximately 30% of AML patients but is absent on normal myeloid and erythroid...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther
Hoofdauteurs: Gomes-Silva, Diogo, Atilla, Erden, Atilla, Pinar Ataca, Mo, Feiyan, Tashiro, Haruko, Srinivasan, Madhuwanti, Lulla, Premal, Rouce, Rayne H., Cabral, Joaquim M.S., Ramos, Carlos A., Brenner, Malcolm K., Mamonkin, Maksim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2019
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318703/
https://ncbi.nlm.nih.gov/pubmed/30391141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.10.001
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