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Comprehensive approach for identifying the T-cell subset origin of CD3 and CD28 antibody-activated chimeric antigen receptor-modified T-cells

The outcome of therapy with CAR-modified T-ells is strongly influenced by the subset origin of the infused T-cells. However, since polyclonally activated T-cells acquire a largely CD45RO(+)CCR7(−) effector memory phenotype after expansion, regardless of subset origin, it is impossible to know which...

詳細記述

保存先:
書誌詳細
出版年:J Immunol
主要な著者: Schmueck-Henneresse, Michael, Omer, Bilal, Shum, Thomas, Tashiro, Haruko, Mamonkin, Maksim, Lapteva, Natalia, Sharma, Sandhya, Rollins, Lisa, Dotti, Gianpietro, Reinke, Petra, Volk, Hans-Dieter, Rooney, Cliona M.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536854/
https://ncbi.nlm.nih.gov/pubmed/28550199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601494
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