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Comprehensive approach for identifying the T-cell subset origin of CD3 and CD28 antibody-activated chimeric antigen receptor-modified T-cells
The outcome of therapy with CAR-modified T-ells is strongly influenced by the subset origin of the infused T-cells. However, since polyclonally activated T-cells acquire a largely CD45RO(+)CCR7(−) effector memory phenotype after expansion, regardless of subset origin, it is impossible to know which...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5536854/ https://ncbi.nlm.nih.gov/pubmed/28550199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601494 |
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