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Chimeric Antigen Receptors for T-Cell Malignancies

Development of chimeric antigen receptor (CAR)-modified T cells for the treatment of T-lineage leukemia and lymphoma has encountered several unique challenges. The most widely expressed tumor antigen targets for malignant T cells are often also expressed on non-malignant T cells. Transducing T cells...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Scherer, Lauren D., Brenner, Malcolm K., Mamonkin, Maksim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411696/
https://ncbi.nlm.nih.gov/pubmed/30891427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00126
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