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Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1

The successful immunotherapy of acute myeloid leukemia (AML) has been hampered because most potential antigenic targets are shared with normal hematopoietic stem cells (HSCs), increasing the risk of sustained and severe hematopoietic toxicity following treatment. C-type lectin-like molecule 1 (CLL-1...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther
Hoofdauteurs: Tashiro, Haruko, Sauer, Tim, Shum, Thomas, Parikh, Kathan, Mamonkin, Maksim, Omer, Bilal, Rouce, Rayne H., Lulla, Premal, Rooney, Cliona M., Gottschalk, Stephen, Brenner, Malcolm K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589064/
https://ncbi.nlm.nih.gov/pubmed/28676343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.05.024
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