Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1

The successful immunotherapy of acute myeloid leukemia (AML) has been hampered because most potential antigenic targets are shared with normal hematopoietic stem cells (HSCs), increasing the risk of sustained and severe hematopoietic toxicity following treatment. C-type lectin-like molecule 1 (CLL-1...

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Vydáno v:Mol Ther
Hlavní autoři: Tashiro, Haruko, Sauer, Tim, Shum, Thomas, Parikh, Kathan, Mamonkin, Maksim, Omer, Bilal, Rouce, Rayne H., Lulla, Premal, Rooney, Cliona M., Gottschalk, Stephen, Brenner, Malcolm K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589064/
https://ncbi.nlm.nih.gov/pubmed/28676343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.05.024
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