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Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1

The successful immunotherapy of acute myeloid leukemia (AML) has been hampered because most potential antigenic targets are shared with normal hematopoietic stem cells (HSCs), increasing the risk of sustained and severe hematopoietic toxicity following treatment. C-type lectin-like molecule 1 (CLL-1...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Ther
Main Authors: Tashiro, Haruko, Sauer, Tim, Shum, Thomas, Parikh, Kathan, Mamonkin, Maksim, Omer, Bilal, Rouce, Rayne H., Lulla, Premal, Rooney, Cliona M., Gottschalk, Stephen, Brenner, Malcolm K.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Gene & Cell Therapy 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589064/
https://ncbi.nlm.nih.gov/pubmed/28676343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.05.024
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