UVB mutagenesis differs in Nras- and Braf-mutant mouse models of melanoma

BRAF-mutant melanomas are more likely than NRAS-mutant melanomas to arise in anatomical locations protected from chronic sun damage. We hypothesized that this discrepancy in tumor location is a consequence of the differential sensitivity of BRAF and NRAS-mutant melanocytes to ultraviolet light (UV)-...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Bowman, Robert L, Hennessey, Rebecca C, Weiss, Tirzah J, Tallman, David A, Crawford, Emma R, Murphy, Brandon M, Webb, Amy, Zhang, Souhui, La Perle, Krista MD, Burd, Craig J, Levine, Ross L, Shain, A Hunter, Burd, Christin E
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321651/
https://ncbi.nlm.nih.gov/pubmed/34210801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202101135
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