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Clinical Correlates of NRAS and BRAF Mutations in Primary Human Melanoma

PURPOSE: NRAS and BRAF mutations are common in cutaneous melanomas, although rarely detected mutually in the same tumor. Distinct clinical correlates of these mutations have not been described, despite in vitro data suggesting enhanced oncogenic effects. This study was designed to test the hypothesi...

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Main Authors: Ellerhorst, Julie A., Greene, Victoria R., Ekmekcioglu, Suhendan, Warneke, Carla L., Johnson, Marcella M., Cooke, Carolyn P., Wang, Li-E, Prieto, Victor G., Gershenwald, Jeffrey E., Wei, Qingyi, Grimm, Elizabeth A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022950/
https://ncbi.nlm.nih.gov/pubmed/20975100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2276
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