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Frequencies of NRAS and BRAF Mutations Increase from the Radial to the Vertical Growth Phase in Cutaneous Melanoma

A lack of consensus exists regarding the relative rates of NRAS and BRAF mutations in the radial (RGP) and vertical (VGP) growth phases of individual melanoma tumors. This study was conducted to test the hypothesis that mutations are acquired with progression from RGP to VGP. Using laser capture mic...

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Detalhes bibliográficos
Main Authors: Greene, Victoria R., Johnson, Marcella M., Grimm, Elizabeth A., Ellerhorst, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741006/
https://ncbi.nlm.nih.gov/pubmed/19037234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.374
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