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UVB mutagenesis differs in Nras- and Braf-mutant mouse models of melanoma
BRAF-mutant melanomas are more likely than NRAS-mutant melanomas to arise in anatomical locations protected from chronic sun damage. We hypothesized that this discrepancy in tumor location is a consequence of the differential sensitivity of BRAF and NRAS-mutant melanocytes to ultraviolet light (UV)-...
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| Izdano u: | Life Sci Alliance |
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| Glavni autori: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Life Science Alliance LLC
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8321651/ https://ncbi.nlm.nih.gov/pubmed/34210801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202101135 |
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