UVB mutagenesis differs in Nras- and Braf-mutant mouse models of melanoma

BRAF-mutant melanomas are more likely than NRAS-mutant melanomas to arise in anatomical locations protected from chronic sun damage. We hypothesized that this discrepancy in tumor location is a consequence of the differential sensitivity of BRAF and NRAS-mutant melanocytes to ultraviolet light (UV)-...

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Bibliografiske detaljer
Udgivet i:Life Sci Alliance
Main Authors: Bowman, Robert L, Hennessey, Rebecca C, Weiss, Tirzah J, Tallman, David A, Crawford, Emma R, Murphy, Brandon M, Webb, Amy, Zhang, Souhui, La Perle, Krista MD, Burd, Craig J, Levine, Ross L, Shain, A Hunter, Burd, Christin E
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321651/
https://ncbi.nlm.nih.gov/pubmed/34210801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202101135
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