CBFB-MYH11 Fusion Sequesters RUNX1 in Cytoplasm to Prevent DNMT3A Recruitment to Target Genes in AML

A growing number of human diseases have been found to be associated with aberrant DNA methylation, including cancer. Mutations targeting genes encoding DNA methyltransferase (DNMT), TET family of DNA demethylases, and isocitrate dehydrogenase (IDH1, IDH2) that produce TET inhibitory metabolite, 2-hy...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Autores principales: Liu, Peng, Liu, Jin-Pin, Sun, Si-Jia, Gao, Yun, Ai, Yingjie, Chen, Xiufei, Sun, Yiping, Zhou, Mengyu, Liu, Yun, Xiong, Yue, Yuan, Hai-Xin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321512/
https://ncbi.nlm.nih.gov/pubmed/34336831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.675424
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares