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RUNX1 Repression Independent Mechanisms of Leukemogenesis by Fusion Genes CBFB-MYH11 and AML1-ETO (RUNX1-RUNX1T1)

The Core Binding Factor (CBF) acute myeloid leukemias (AMLs) are a prognostically distinct subgroup that includes patients with the inv(16) and t(8:21) chromosomal rearrangements. Both of these rearrangements result in the formation of fusion proteins, CBFB-MYH11 and AML1-ETO respectively, that invo...

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Autors principals: Hyde, R. Katherine, Liu, P. Paul
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298446/
https://ncbi.nlm.nih.gov/pubmed/20589720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22596
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