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Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II

The development of unnatural base pairs (UBPs) has greatly increased the information storage capacity of DNA, allowing for transcription of unnatural RNA by the heterologously expressed T7 RNA polymerase (RNAP) in Escherichia coli. However, little is known about how UBPs are transcribed by cellular...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Chem Biol
Hauptverfasser: Oh, Juntaek, Shin, Ji, Unarta, Ilona Christy, Wang, Wei, Feldman, Aaron W., Karadeema, Rebekah J., Xu, Liang, Xu, Jun, Chong, Jenny, Krishnamurthy, Ramanarayanan, Huang, Xuhui, Romesberg, Floyd E., Wang, Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319059/
https://ncbi.nlm.nih.gov/pubmed/34140682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-021-00817-3
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