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Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II

The development of unnatural base pairs (UBPs) has greatly increased the information storage capacity of DNA, allowing for transcription of unnatural RNA by the heterologously expressed T7 RNA polymerase (RNAP) in Escherichia coli. However, little is known about how UBPs are transcribed by cellular...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Oh, Juntaek, Shin, Ji, Unarta, Ilona Christy, Wang, Wei, Feldman, Aaron W., Karadeema, Rebekah J., Xu, Liang, Xu, Jun, Chong, Jenny, Krishnamurthy, Ramanarayanan, Huang, Xuhui, Romesberg, Floyd E., Wang, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319059/
https://ncbi.nlm.nih.gov/pubmed/34140682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-021-00817-3
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