Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains

The p75 neurotrophin receptor (p75(NTR)) is a critical mediator of neuronal death and tissue remodeling and has been implicated in various neurodegenerative diseases and cancers. The death domain (DD) of p75(NTR) is an intracellular signaling hub and has been shown to interact with diverse adaptor p...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Zhang, Ning, Kisiswa, Lilian, Ramanujan, Ajeena, Li, Zhen, Sim, Eunice Weiling, Tian, Xianbin, Yuan, Wensu, Ibáñez, Carlos F., Lin, Zhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318917/
https://ncbi.nlm.nih.gov/pubmed/34175311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100916
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