Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains

The p75 neurotrophin receptor (p75(NTR)) is a critical mediator of neuronal death and tissue remodeling and has been implicated in various neurodegenerative diseases and cancers. The death domain (DD) of p75(NTR) is an intracellular signaling hub and has been shown to interact with diverse adaptor p...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Ning, Kisiswa, Lilian, Ramanujan, Ajeena, Li, Zhen, Sim, Eunice Weiling, Tian, Xianbin, Yuan, Wensu, Ibáñez, Carlos F., Lin, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318917/
https://ncbi.nlm.nih.gov/pubmed/34175311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100916
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