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Structural basis of death domain signaling in the p75 neurotrophin receptor
Death domains (DDs) mediate assembly of oligomeric complexes for activation of downstream signaling pathways through incompletely understood mechanisms. Here we report structures of complexes formed by the DD of p75 neurotrophin receptor (p75(NTR)) with RhoGDI, for activation of the RhoA pathway, wi...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4739766/ https://ncbi.nlm.nih.gov/pubmed/26646181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11692 |
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