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Structural basis of death domain signaling in the p75 neurotrophin receptor

Death domains (DDs) mediate assembly of oligomeric complexes for activation of downstream signaling pathways through incompletely understood mechanisms. Here we report structures of complexes formed by the DD of p75 neurotrophin receptor (p75(NTR)) with RhoGDI, for activation of the RhoA pathway, wi...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Lin, Zhi, Tann, Jason Y, Goh, Eddy TH, Kelly, Claire, Lim, Kim Buay, Gao, Jian Fang, Ibanez, Carlos F
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739766/
https://ncbi.nlm.nih.gov/pubmed/26646181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11692
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