Structural basis of death domain signaling in the p75 neurotrophin receptor

Death domains (DDs) mediate assembly of oligomeric complexes for activation of downstream signaling pathways through incompletely understood mechanisms. Here we report structures of complexes formed by the DD of p75 neurotrophin receptor (p75(NTR)) with RhoGDI, for activation of the RhoA pathway, wi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Lin, Zhi, Tann, Jason Y, Goh, Eddy TH, Kelly, Claire, Lim, Kim Buay, Gao, Jian Fang, Ibanez, Carlos F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2015
Gaiak:
Biochemistry
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739766/
https://ncbi.nlm.nih.gov/pubmed/26646181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11692
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