Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma

BACKGROUND. The frequency of "exhausted" or check-point-positive (PD-1(+)CTLA-4(+)) cytotoxic lymphocytes (Tex) in the tumor microenvironment is associated with response to anti-PD-1 therapy in metastatic melanoma. The current study determined whether pretreatment Tex cells in locally adva...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Ann Surg Oncol
Autores principales: Levine, Lauren S., Mahuron, Kelly M., Tsai, Katy K., Wu, Clinton, Mattis, Daiva M., Pauli, Mariela L., Oglesby, Arielle, Lee, James C., Spitzer, Matthew H., Krummel, Matthew F., Algazi, Alain P., Rosenblum, Michael D., Alvarado, Michael, Daud, Adil I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317618/
https://ncbi.nlm.nih.gov/pubmed/32488521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-020-08648-7
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares