Tumor immune profiling predicts response to anti–PD-1 therapy in human melanoma

BACKGROUND. Immune checkpoint blockade is revolutionizing therapy for advanced cancer, but many patients do not respond to treatment. The identification of robust biomarkers that predict clinical response to specific checkpoint inhibitors is critical in order to stratify patients and to rationally s...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Daud, Adil I., Loo, Kimberly, Pauli, Mariela L., Sanchez-Rodriguez, Robert, Sandoval, Priscila Munoz, Taravati, Keyon, Tsai, Katy, Nosrati, Adi, Nardo, Lorenzo, Alvarado, Michael D., Algazi, Alain P., Pampaloni, Miguel H., Lobach, Iryna V., Hwang, Jimmy, Pierce, Robert H., Gratz, Iris K., Krummel, Matthew F., Rosenblum, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004965/
https://ncbi.nlm.nih.gov/pubmed/27525433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87324
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