Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma

BACKGROUND. The frequency of "exhausted" or check-point-positive (PD-1(+)CTLA-4(+)) cytotoxic lymphocytes (Tex) in the tumor microenvironment is associated with response to anti-PD-1 therapy in metastatic melanoma. The current study determined whether pretreatment Tex cells in locally adva...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ann Surg Oncol
Päätekijät: Levine, Lauren S., Mahuron, Kelly M., Tsai, Katy K., Wu, Clinton, Mattis, Daiva M., Pauli, Mariela L., Oglesby, Arielle, Lee, James C., Spitzer, Matthew H., Krummel, Matthew F., Algazi, Alain P., Rosenblum, Michael D., Alvarado, Michael, Daud, Adil I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317618/
https://ncbi.nlm.nih.gov/pubmed/32488521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-020-08648-7
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