Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury

RATIONALE: Reperfusion injury accounts for up to half of myocardial infarct size, and meaningful clinical therapies targeting it do not exist. We have reported previously that autophagy is reduced during reperfusion and that HDAC inhibition enhances cardiomyocyte autophagy and blunts ischemia/reperf...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Xie, Min, Cho, Geoffrey W., Kong, Yongli, Li, Dan L., Altamirano, Francisco, Luo, Xiang, Morales, Cyndi R., Jiang, Nan, Schiattarella, Gabriele G., May, Herman I., Medina, Jessica, Shelton, John, Ferdous, Anwarul, Gillette, Thomas G., Hill, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317428/
https://ncbi.nlm.nih.gov/pubmed/34111934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318601
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