Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury

RATIONALE: Reperfusion injury accounts for up to half of myocardial infarct size, and meaningful clinical therapies targeting it do not exist. We have reported previously that autophagy is reduced during reperfusion and that HDAC inhibition enhances cardiomyocyte autophagy and blunts ischemia/reperf...

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Vydáno v:Circ Res
Hlavní autoři: Xie, Min, Cho, Geoffrey W., Kong, Yongli, Li, Dan L., Altamirano, Francisco, Luo, Xiang, Morales, Cyndi R., Jiang, Nan, Schiattarella, Gabriele G., May, Herman I., Medina, Jessica, Shelton, John, Ferdous, Anwarul, Gillette, Thomas G., Hill, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317428/
https://ncbi.nlm.nih.gov/pubmed/34111934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318601
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