Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury

RATIONALE: Reperfusion injury accounts for up to half of myocardial infarct size, and meaningful clinical therapies targeting it do not exist. We have reported previously that autophagy is reduced during reperfusion and that HDAC inhibition enhances cardiomyocyte autophagy and blunts ischemia/reperf...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Circ Res
Prif Awduron: Xie, Min, Cho, Geoffrey W., Kong, Yongli, Li, Dan L., Altamirano, Francisco, Luo, Xiang, Morales, Cyndi R., Jiang, Nan, Schiattarella, Gabriele G., May, Herman I., Medina, Jessica, Shelton, John, Ferdous, Anwarul, Gillette, Thomas G., Hill, Joseph A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317428/
https://ncbi.nlm.nih.gov/pubmed/34111934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318601
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg