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Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury

RATIONALE: Reperfusion injury accounts for up to half of myocardial infarct size, and meaningful clinical therapies targeting it do not exist. We have reported previously that autophagy is reduced during reperfusion and that HDAC inhibition enhances cardiomyocyte autophagy and blunts ischemia/reperf...

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Dades bibliogràfiques
Publicat a:Circ Res
Autors principals: Xie, Min, Cho, Geoffrey W., Kong, Yongli, Li, Dan L., Altamirano, Francisco, Luo, Xiang, Morales, Cyndi R., Jiang, Nan, Schiattarella, Gabriele G., May, Herman I., Medina, Jessica, Shelton, John, Ferdous, Anwarul, Gillette, Thomas G., Hill, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317428/
https://ncbi.nlm.nih.gov/pubmed/34111934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318601
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