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The molecular context of vulnerability for CDK9 suppression in triple wild-type melanoma
Approximately half of melanoma tumors lack a “druggable” target and are unresponsive to current targeted therapeutics. One proposed approach for treating these therapeutically-orphaned tumors is by targeting transcriptional dependencies (“oncogene starvation”), whereby survival factors are depleted...
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| Publié dans: | J Invest Dermatol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8316294/ https://ncbi.nlm.nih.gov/pubmed/33745909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.12.035 |
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