Vemurafenib Synergizes with Nutlin-3 to Deplete Survivin and Suppress Melanoma Viability and Tumor Growth

BACKGROUND: For patients with advanced melanoma, primary and secondary resistance to selective BRAF inhibition remains one of the most critically compelling challenges. One rationale argues that novel biologically-informed strategies are needed to maximally cripple melanoma cells up front before com...

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Bibliografiske detaljer
Main Authors: Ji, Zhenyu, Kumar, Raj, Taylor, Michael, Rajadurai, Anpuchchelvi, Marzuka-Alcalá, Alexander, Chen, Y. Erin, Njauw, Ching-Ni Jenny, Flaherty, Keith, Jönsson, Goran, Tsao, Hensin
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777641/
https://ncbi.nlm.nih.gov/pubmed/23812671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0074
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