Growth suppression by dual BRAF(V600E) and NRAS(Q61) oncogene expression is mediated by SPRY4 in melanoma

The underlying forces that shape mutational patterns within any type of cancer have been poorly characterized. One of the best preserved exclusionary relationships is that between BRAF(V600E) and NRAS(Q61) in melanomas. To explore possible mechanisms which could explain this phenomenon, we overexpre...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Kumar, Raj, Njauw, Ching-Ni, Reddy, Bobby Y., Ji, Zhenyu, Rajadurai, Anpuchchelvi, Klebanov, Nikolai, Tsao, Hensin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756020/
https://ncbi.nlm.nih.gov/pubmed/30651601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0632-2
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