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Targeting the RAS pathway in melanoma

Metastatic melanoma is a highly lethal type of skin cancer and is often refractory to all traditional chemo-therapeutic agents. Key insights into the genetic makeup of melanoma tumors have led to the development of promising targeted agents. An activated RAS pathway, anchored by oncogenic BRAF, appe...

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Detalhes bibliográficos
Main Authors: Ji, Zhenyu, Flaherty, Keith T., Tsao, Hensin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759017/
https://ncbi.nlm.nih.gov/pubmed/21962474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.08.001
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