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Increased demand for NAD+ relative to ATP drives aerobic glycolysis
Aerobic glycolysis, or preferential fermentation of glucose-derived pyruvate to lactate despite available oxygen, is associated with proliferation across many organisms and conditions. To better understand this association, we examined the metabolic consequence of activating the pyruvate dehydrogena...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Cell |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8315838/ https://ncbi.nlm.nih.gov/pubmed/33382985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.12.012 |
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