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Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane

BACKGROUND: Cancer cells, and a variety of normal cells, exhibit aerobic glycolysis, high rates of glucose fermentation in the presence of normal oxygen concentrations, also known as the Warburg effect. This metabolism is considered abnormal because it violates the standard model of cellular energy...

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Bibliographic Details
Main Authors: Epstein, Tamir, Xu, Liping, Gillies, Robert J, Gatenby, Robert A
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060846/
https://ncbi.nlm.nih.gov/pubmed/24982758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-2-7
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