KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia

The cellular adaptive response to hypoxia, mediated by high HIF1α levels includes metabolic reprogramming, restricted DNA replication and cell division. In contrast to healthy cells, the genome of cancer cells, and Kaposi’s sarcoma associated herpesvirus (KSHV) infected cells maintains replication i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Kumar Singh, Rajnish, Pei, Yonggang, Bose, Dipayan, Lamplugh, Zachary L, Sun, Kunfeng, Yuan, Yan, Lieberman, Paul, You, Jianxin, Robertson, Erle S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2021
Gaiak:
Microbiology and Infectious Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315796/
https://ncbi.nlm.nih.gov/pubmed/34279223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57436
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