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KSHV requires vCyclin to overcome replicative senescence in primary human lymphatic endothelial cells

Kaposi’s Sarcoma Herpesvirus (KSHV) is present in the main tumor cells of Kaposi’s Sarcoma (KS), the spindle cells, which are of endothelial origin. KSHV is also associated with two B-cell lymphomas, Primary Effusion Lymphoma (PEL) and Multicentric Castleman’s Disease. In KS and PEL, KSHV is primari...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: DiMaio, Terri A., Vogt, Daniel T., Lagunoff, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326280/
https://ncbi.nlm.nih.gov/pubmed/32555637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008634
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