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KSHV requires vCyclin to overcome replicative senescence in primary human lymphatic endothelial cells

Kaposi’s Sarcoma Herpesvirus (KSHV) is present in the main tumor cells of Kaposi’s Sarcoma (KS), the spindle cells, which are of endothelial origin. KSHV is also associated with two B-cell lymphomas, Primary Effusion Lymphoma (PEL) and Multicentric Castleman’s Disease. In KS and PEL, KSHV is primari...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: DiMaio, Terri A., Vogt, Daniel T., Lagunoff, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326280/
https://ncbi.nlm.nih.gov/pubmed/32555637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008634
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