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KSHV requires vCyclin to overcome replicative senescence in primary human lymphatic endothelial cells

Kaposi’s Sarcoma Herpesvirus (KSHV) is present in the main tumor cells of Kaposi’s Sarcoma (KS), the spindle cells, which are of endothelial origin. KSHV is also associated with two B-cell lymphomas, Primary Effusion Lymphoma (PEL) and Multicentric Castleman’s Disease. In KS and PEL, KSHV is primari...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: DiMaio, Terri A., Vogt, Daniel T., Lagunoff, Michael
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326280/
https://ncbi.nlm.nih.gov/pubmed/32555637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008634
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