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KSHV requires vCyclin to overcome replicative senescence in primary human lymphatic endothelial cells

Kaposi’s Sarcoma Herpesvirus (KSHV) is present in the main tumor cells of Kaposi’s Sarcoma (KS), the spindle cells, which are of endothelial origin. KSHV is also associated with two B-cell lymphomas, Primary Effusion Lymphoma (PEL) and Multicentric Castleman’s Disease. In KS and PEL, KSHV is primari...

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Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: DiMaio, Terri A., Vogt, Daniel T., Lagunoff, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326280/
https://ncbi.nlm.nih.gov/pubmed/32555637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008634
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