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KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia
The cellular adaptive response to hypoxia, mediated by high HIF1α levels includes metabolic reprogramming, restricted DNA replication and cell division. In contrast to healthy cells, the genome of cancer cells, and Kaposi’s sarcoma associated herpesvirus (KSHV) infected cells maintains replication i...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8315796/ https://ncbi.nlm.nih.gov/pubmed/34279223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57436 |
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